Public Broadcasting Service - Love To Catalyze/Choppin' Tags lyrics

CHORUS Just gonna float, looking for a substrate If I find it then I will accelerate As long as it's the right shape and size I'll help it react because I love to catalyze I love to catalyze VERSE Life's impossible without me Won't go quick enough without an enzyme I'm a protein that find substrates. And I'm Helping them traaaaansform into prod-ucts - in time As long as their size is right for my active site (pause).... Wait some milliseconds. You'll see It's like a lock and key, I change but don't get changed. Still me ...Which means that I can get recycled so I can keep Speed-ing up reactions unless I get de (natured) What happened!?.... We're changing temp... There goes my shape! I'm just a glob, can't do my job, so I'm feeling lame My conformation's strange. I'm no longer in my range Back at body temperature things were going great I can no longer work these substrates - I'm so ashamed Oh snap- is that the whole point of homeo-stay(sis)? Stay in the right zone - don't go so high or low again I guess you don't know your own strength CHORUS Just gonna float, looking for a substrate And if I find it then I will accelerate As long as it's the right shape and size I'll help it react because I love to catalyze I love to catalyze Transition Dialogue Human: OK I get it. You speed up reactions and you're the reason I am alive. What have you done for me lately? Enzyme: Really? That's not enough for you? I'll let my buddy restriction enzyme tell you about what he does. Hey, can we go to the bio lab? "CHOP SOME TAGS" CHORUS I'm gonna chop some TAGs When I recognize that sequence I'mma lop it I - I - I'm huntin'. See it - I'mma cut it Snip and cut and chop 'em VERSE Nah, Roll up to the strand like, "What up, here comes a big chop" All this DNA just waiting here to be cropped ....I'm bacteria's natural defenda Cut backbones like an enzyme ninja Rollin' in, clippin' T's, cleaving 'tween C and G's Only certain nucs though -- slicin' up specifically Recognize 4-8 base pairs typically Blunt ends kinda smooth. But if I cut it jagged-y It Stiickkksssssssss All because of those sticky ends (cut it!) Choppin' it, changin it, askin' "why is this even relevant?" I'm the key to those biotech tools everybody been sellin' ya DNA fingerprintin'? Need an enzyme like me Solvin' crimes - RFLPs at the crime scene I'mma cut that gene out, I'mma cut that gene out Take it from a jellyfish - put it in a cat - Meow (thank you!) Can't see the point of a cat with a green glow? What about bacteria makin insulin though? Corn needs some carotene? Give that corn some carotene E. Coli makin that? Now it's making gasoline! I'm just a - nuc - le-ase makin incisions You humans are the ones makin' decisions You can make almost anything that you envision But think about the consequences 'for I get to snippin' B'fore I get to snippin' B'fore I get to snippin' B'fore I get to snippin'