1. In transmitting simultaneously to the Security Council and the General Assembly the report on the incident which took place on 21 August 2013 in the Ghouta area of Damascus (see annex), the Secretary-General expresses his profound shock and regret at the conclusion that chemical weapons were used on a relatively large scale, resulting in numerous casualties, particularly among civilians and including many children. The Secretary-General condemns in the strongest possible terms the use of chemical weapons and believes that this act is a war crime and grave violation of the 1925 Protocol for the Prohibition of the Use in War of Asphyxiating, Poisonous or Other Gases, and of Bacteriological Methods of Warfare and other relevant rules of customary international law. The international community has a moral responsibility to hold accountable those responsible and for ensuring that chemical weapons can never re-emerge as an instrument of warfare. 2. The Secretary-General wishes to express his deep appreciation to the Head and members of the Mission, including the dedicated teams of experts from the Organisation for the Prohibition of Chemical Weapons and the World Health Organization. The Secretary-General is grateful for the support provided by Member States. The Secretary-General counts on the continued support of all concerned until the Mission completes its investigation into all other allegations and submits its final report. 3. The accession of the Syrian Arab Republic on 14 September 2013 to the Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons and on their Destruction is a welcome development. As depositary of the Convention, the Secretary-General has long called for its universality. The Secretary-General welcomes the agreement reached on 14 September 2013 between the Russian Federation and the United States of America on a framework for the elimination of chemical weapons in the Syrian Arab Republic. He hopes that the Executive Council of the Organisation for the Prohibition of Chemical Weapons and the United Nations Security Council quickly move to consider and implement this proposal, which is aimed at expediting the fufillment of the obligations of the Syrian Arab Republic under the Convention. The Secretary-General calls upon the Syrian Arab Republic to implement faithfully all of its disarmament obligations and he stands ready to facilitate international efforts aimed at providing a**istance in this regard. 4. The Secretary-General reiterates that any use of chemical weapons by anyone under any circumstances is a grave violation of international law. 5. Where there are allegations of the use of chemical weapons, however, the international community looks to the United Nations for an impartial and objective determination whether, and to what extent, such allegations can be substantiated. It is imperative therefore that the authority extended to the Secretary-General by the General Assembly (A/RES/42/37 C) and endorsed by the Security Council (S/RES/620 (1988)) continues to be respected and that the mechanism related thereto continues to be strengthened. The Secretary-General believes that an effective mechanism to investigate allegations of the use of chemical weapons can serve as an important deterrent against their employment.